Chronic Renal Transplant Rejection and Possible Anti-Proliferative Drug Targets
نویسندگان
چکیده
منابع مشابه
Chronic Renal Transplant Rejection and Possible Anti-Proliferative Drug Targets
The global prevalence of renal transplants is increasing with time, and renal transplantation is the only definite treatment for end-stage renal disease. We have limited the acute and late acute rejection of kidney allografts, but the long-term survival of renal tissues still remains a difficult and unanswered question as most of the renal transplants undergo failure within a decade of their tr...
متن کاملRenal Transplant Rejection
Introduction: Determining if the cause of renal allograft dysfunction in the early post transplant period is due to rejection or other reasons is a daunting task for the clinician. Clinical signs and symptoms alone are not helpful in clearly distinguishing the numerous causes of renal dysfunction. Various noninvasive tests including imaging studies have also been unsuccessful in distinguishing ...
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This 43-year-old Caucasian female presented in a septic condition in the emergency room. At the time of admission her temperature was 38.5 Celsius, white blood cells (WBC) 12800, red blood cells 3.8 mill, hemoglobin 10.8, hematocrit 36, urea 28 mg/dl, serum creatinine 3.2 mg/dl, K 5.8 meq/l, Na 128 meq/ l, alk ptsa 142 U/l. Urine analysis 50 WBC/hpf, innumerable bacteria/hpf, cellular debries, ...
متن کاملTransplant capillaropathy and transplant glomerulopathy: ultrastructural markers of chronic renal allograft rejection.
A late dysfunction of a renal allograft refers to a progressive decline in renal function manifested)3 months after transplantation. A late dysfunction may have several causes, such as chronic rejection, chronic allograft nephropathy, chronic calcineurin inhibitor toxicity, de novo or recurrent renal disease and acute rejection. An allograft biopsy is necessary to establish a definitive diagnos...
متن کاملAssociation between Amylase Excretion Fraction and Acute Renal Transplant Rejection in Pediatrics
Background and Objectives: Serum amylase increases and its excretion fraction decreases in patients with renal failure. Excretion fraction can be used as a diagnostic way in individuals with acute renal transplant rejection. In this study, the association between amylase excretion fraction and acute renal transplant rejection, was investigated in pediatrics. Methods: in this case - control s...
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ژورنال
عنوان ژورنال: Cureus
سال: 2015
ISSN: 2168-8184
DOI: 10.7759/cureus.376